Mickey C. McGuire (born January 18, 1941) is an American former professional baseball player. He was a second baseman/shortstop in Major League Baseball who played for the Baltimore Orioles in the 1962 and 1967 seasons. Listed at 5 feet 10 inches (1.78 m), 170 pounds (77 kg), McGuire batted and threw right-handed. He was born in Dayton, Ohio.
In a two-season career, McGuire was a .190 hitter (4-for-21) with two runs and two RBI in 16 games. He did not register an extra-base hit.