John Lackey
| Date | Team | Opponent | Result | IP | H | R | ER | BB | SO | PA | 2B | 3B | HR | GO | FO | MISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2010-04-07 | BOS | vs. NYY | L, 3-1 | 6.0 | 3 | 0 | 0 | 2 | 3 | 22 | 0 | 0 | 0 | 8 | 5 | SP |
| 2010-04-14 | BOS | @ MIN | W, 6-3 | 6.2 | 7 | 2 | 2 | 4 | 2 | 29 | 1 | 0 | 0 | 5 | 11 | SP, W |
| 2010-04-19 | BOS | vs. TBR | L, 8-2 | 3.1 | 9 | 8 | 8 | 1 | 3 | 19 | 3 | 1 | 1 | 4 | 1 | SP, L |
| 2010-04-24 | BOS | vs. BAL | W, 7-6 | 7.0 | 10 | 3 | 3 | 2 | 3 | 31 | 1 | 0 | 1 | 7 | 9 | SP, W |
| 2010-04-30 | BOS | @ BAL | L, 5-4 | 7.0 | 6 | 3 | 2 | 3 | 6 | 28 | 1 | 0 | 0 | 6 | 6 | SP |
| 2010-05-05 | BOS | vs. LAA | W, 3-1 | 7.0 | 2 | 1 | 1 | 2 | 4 | 25 | 0 | 0 | 1 | 12 | 4 | SP, W |
| 2010-05-10 | BOS | vs. TOR | W, 7-6 | 6.0 | 8 | 6 | 6 | 3 | 6 | 29 | 2 | 0 | 1 | 7 | 4 | SP, W |
| 2010-05-16 | BOS | @ DET | L, 5-1 | 7.0 | 9 | 5 | 5 | 4 | 4 | 32 | 0 | 0 | 1 | 2 | 13 | SP, L |
| 2010-05-21 | BOS | @ PHI | L, 5-1 | 5.0 | 6 | 4 | 4 | 5 | 3 | 26 | 2 | 0 | 2 | 4 | 8 | SP, L |
| 2010-05-26 | BOS | @ TBR | W, 11-3 | 6.1 | 8 | 2 | 2 | 4 | 1 | 31 | 2 | 0 | 0 | 11 | 6 | SP, W |
| 2010-06-01 | BOS | vs. OAK | W, 9-4 | 6.0 | 12 | 4 | 4 | 2 | 4 | 32 | 4 | 1 | 1 | 5 | 9 | SP, W |
| 2010-06-06 | BOS | @ BAL | L, 4-3 | 7.0 | 7 | 2 | 2 | 3 | 2 | 31 | 2 | 0 | 0 | 10 | 7 | SP |
| 2010-06-11 | BOS | vs. PHI | W, 12-2 | 7.0 | 6 | 2 | 2 | 0 | 3 | 27 | 2 | 0 | 0 | 11 | 6 | SP, W |
| 2010-06-17 | BOS | vs. ARI | W, 8-5 | 6.0 | 8 | 4 | 3 | 2 | 5 | 28 | 3 | 0 | 0 | 7 | 5 | SP, W |
| 2010-06-23 | BOS | @ COL | L, 8-6 | 6.2 | 10 | 5 | 5 | 0 | 7 | 29 | 2 | 1 | 1 | 8 | 4 | SP |
| 2010-06-29 | BOS | vs. TBR | W, 8-5 | 7.0 | 8 | 1 | 1 | 2 | 3 | 30 | 1 | 0 | 0 | 6 | 11 | SP, W |
| 2010-07-04 | BOS | vs. BAL | L, 6-1 | 7.1 | 8 | 4 | 3 | 1 | 7 | 32 | 3 | 0 | 0 | 10 | 4 | SP, L |
| 2010-07-10 | BOS | @ TOR | L, 9-5 | 4.2 | 8 | 7 | 7 | 6 | 2 | 28 | 4 | 0 | 1 | 4 | 8 | SP, L |
| 2010-07-17 | BOS | vs. TEX | W, 3-2 | 7.0 | 7 | 2 | 2 | 2 | 3 | 28 | 1 | 0 | 0 | 12 | 4 | SP |
| 2010-07-22 | BOS | @ SEA | W, 8-6 | 8.0 | 2 | 1 | 0 | 1 | 6 | 28 | 0 | 0 | 0 | 6 | 11 | SP |
| 2010-07-27 | BOS | @ LAA | W, 4-2 | 7.1 | 7 | 2 | 2 | 1 | 4 | 30 | 2 | 0 | 1 | 10 | 5 | SP, W |
| 2010-08-02 | BOS | vs. CLE | L, 6-5 | 5.1 | 9 | 6 | 6 | 5 | 7 | 28 | 4 | 0 | 0 | 5 | 2 | SP, L |
| 2010-08-07 | BOS | @ NYY | L, 5-2 | 6.0 | 8 | 5 | 5 | 3 | 7 | 29 | 0 | 1 | 0 | 6 | 5 | SP, L |
| 2010-08-12 | BOS | @ TOR | L, 6-5 | 8.0 | 8 | 3 | 3 | 1 | 4 | 30 | 3 | 0 | 1 | 7 | 10 | SP |
| 2010-08-18 | BOS | vs. LAA | W, 7-5 | 7.0 | 10 | 5 | 5 | 0 | 5 | 28 | 4 | 0 | 2 | 9 | 4 | SP, W |
| 2010-08-23 | BOS | vs. SEA | W, 6-3 | 8.0 | 6 | 3 | 2 | 2 | 10 | 32 | 0 | 0 | 0 | 8 | 4 | SP, W |
| 2010-08-29 | BOS | @ TBR | L, 5-3 | 6.1 | 9 | 5 | 5 | 3 | 7 | 29 | 1 | 0 | 2 | 8 | 2 | SP, L |
| 2010-09-04 | BOS | vs. CHW | L, 3-1 | 7.0 | 4 | 3 | 1 | 2 | 7 | 29 | 1 | 1 | 0 | 2 | 11 | SP, L |
| 2010-09-11 | BOS | @ OAK | L, 4-3 | 7.0 | 6 | 3 | 3 | 0 | 6 | 26 | 2 | 1 | 0 | 9 | 5 | SP, L |
| 2010-09-17 | BOS | vs. TOR | L, 11-9 | 4.1 | 8 | 7 | 6 | 2 | 3 | 25 | 4 | 0 | 0 | 3 | 6 | SP, L |
| 2010-09-22 | BOS | vs. BAL | W, 6-1 | 7.0 | 5 | 1 | 1 | 0 | 4 | 25 | 2 | 0 | 0 | 10 | 6 | SP, W |
| 2010-09-28 | BOS | @ CHW | L, 5-4 | 6.0 | 3 | 2 | 2 | 2 | 5 | 23 | 1 | 0 | 1 | 3 | 9 | SP |
| 2010-10-03 | BOS | vs. NYY | W, 8-4 | 7.2 | 6 | 3 | 2 | 2 | 10 | 31 | 1 | 0 | 1 | 7 | 5 | SP, W |
| Total Games: 33 | ||||||||||||||||