Johan Santana
| Date | Team | Opponent | Result | IP | H | R | ER | BB | SO | PA | 2B | 3B | HR | GO | FO | MISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2010-04-05 | NYM | vs. FLA | W, 7-1 | 6.0 | 4 | 1 | 1 | 2 | 5 | 24 | 1 | 0 | 0 | 2 | 10 | SP, W |
| 2010-04-11 | NYM | vs. WAS | L, 5-2 | 5.0 | 5 | 5 | 5 | 3 | 3 | 22 | 1 | 1 | 1 | 3 | 6 | SP, L |
| 2010-04-17 | NYM | @ STL | W, 2-1 | 7.0 | 4 | 0 | 0 | 1 | 9 | 26 | 1 | 0 | 0 | 4 | 7 | SP |
| 2010-04-22 | NYM | vs. CHC | W, 5-2 | 6.1 | 8 | 1 | 1 | 0 | 5 | 27 | 2 | 0 | 0 | 3 | 9 | SP, W |
| 2010-04-27 | NYM | vs. LAD | W, 4-0 | 6.0 | 4 | 0 | 0 | 3 | 6 | 25 | 0 | 1 | 0 | 6 | 6 | SP, W |
| 2010-05-02 | NYM | @ PHI | L, 11-5 | 3.2 | 8 | 10 | 10 | 2 | 1 | 21 | 1 | 0 | 4 | 6 | 4 | SP, L |
| 2010-05-08 | NYM | vs. SFG | W, 5-4 | 7.2 | 8 | 4 | 4 | 0 | 6 | 30 | 0 | 0 | 0 | 5 | 11 | SP |
| 2010-05-13 | NYM | @ FLA | L, 2-1 | 7.0 | 6 | 1 | 0 | 1 | 5 | 27 | 1 | 0 | 0 | 8 | 6 | SP |
| 2010-05-18 | NYM | @ ATL | L, 3-2 | 7.0 | 5 | 2 | 2 | 2 | 4 | 28 | 0 | 0 | 1 | 9 | 8 | SP |
| 2010-05-23 | NYM | vs. NYY | W, 6-4 | 7.2 | 6 | 1 | 1 | 3 | 5 | 31 | 0 | 0 | 0 | 6 | 11 | SP, W |
| 2010-05-28 | NYM | @ MIL | L, 2-0 | 8.0 | 3 | 0 | 0 | 2 | 5 | 29 | 1 | 0 | 0 | 2 | 16 | SP |
| 2010-06-02 | NYM | @ SDP | L, 5-1 | 7.0 | 5 | 0 | 0 | 5 | 3 | 30 | 0 | 0 | 0 | 6 | 9 | SP |
| 2010-06-10 | NYM | vs. SDP | L, 4-2 | 6.2 | 8 | 4 | 4 | 4 | 1 | 29 | 2 | 0 | 0 | 8 | 8 | SP, L |
| 2010-06-15 | NYM | @ CLE | W, 7-6 | 7.0 | 7 | 4 | 4 | 2 | 1 | 29 | 1 | 0 | 1 | 6 | 11 | SP, W |
| 2010-06-20 | NYM | @ NYY | L, 4-0 | 6.0 | 8 | 4 | 4 | 1 | 3 | 27 | 1 | 1 | 1 | 8 | 6 | SP, L |
| 2010-06-26 | NYM | vs. MIN | L, 6-0 | 6.0 | 8 | 5 | 5 | 2 | 4 | 26 | 4 | 0 | 0 | 5 | 6 | SP, L |
| 2010-07-01 | NYM | @ WAS | L, 2-1 | 7.0 | 6 | 1 | 1 | 2 | 7 | 29 | 1 | 0 | 0 | 3 | 9 | SP |
| 2010-07-06 | NYM | vs. CIN | W, 3-0 | 9.0 | 3 | 0 | 0 | 3 | 5 | 34 | 1 | 0 | 0 | 6 | 15 | SP, W, CG, SHO |
| 2010-07-11 | NYM | vs. ATL | W, 3-0 | 7.0 | 5 | 0 | 0 | 3 | 5 | 29 | 1 | 0 | 0 | 2 | 13 | SP, W |
| 2010-07-18 | NYM | @ SFG | W, 4-3 | 8.0 | 8 | 1 | 1 | 1 | 5 | 32 | 2 | 0 | 0 | 9 | 9 | SP |
| 2010-07-23 | NYM | @ LAD | W, 6-1 | 7.0 | 5 | 1 | 1 | 1 | 4 | 27 | 1 | 0 | 0 | 6 | 11 | SP, W |
| 2010-07-28 | NYM | vs. STL | L, 8-7 | 5.2 | 13 | 7 | 7 | 1 | 2 | 31 | 2 | 0 | 1 | 5 | 10 | SP |
| 2010-08-02 | NYM | @ ATL | L, 4-1 | 7.0 | 9 | 4 | 4 | 2 | 11 | 32 | 4 | 0 | 1 | 4 | 5 | SP, L |
| 2010-08-07 | NYM | @ PHI | W, 1-0 | 7.1 | 5 | 0 | 0 | 3 | 6 | 30 | 1 | 0 | 0 | 3 | 10 | SP, W |
| 2010-08-12 | NYM | vs. COL | W, 4-0 | 9.0 | 4 | 0 | 0 | 2 | 10 | 32 | 0 | 0 | 0 | 4 | 12 | SP, W, CG, SHO |
| 2010-08-17 | NYM | @ HOU | L, 4-3 | 8.0 | 9 | 4 | 4 | 1 | 7 | 32 | 3 | 0 | 2 | 9 | 6 | SP, L, CG |
| 2010-08-22 | NYM | @ PIT | L, 2-1 | 8.0 | 4 | 2 | 2 | 1 | 9 | 28 | 0 | 0 | 2 | 3 | 10 | SP, L, CG |
| 2010-08-28 | NYM | vs. HOU | L, 4-1 | 7.0 | 8 | 4 | 4 | 1 | 4 | 31 | 0 | 0 | 1 | 8 | 8 | SP, L |
| 2010-09-02 | NYM | @ ATL | W, 4-2 | 5.0 | 3 | 1 | 1 | 1 | 3 | 19 | 0 | 0 | 1 | 5 | 5 | SP, W |
| Total Games: 29 | ||||||||||||||||