George Pepper Prentiss (a.k.a. George Pepper Wilson) (June 10, 1876 – September 23, 1902) was a pitcher in Major League Baseball who played from 1901 through 1902 for the Boston Americans (1901–02) and Baltimore Orioles (1902). Listed at 5 ft 11 in (1.80 m), 175 lb., Prentiss was a switch-hitter and threw right-handed. He was born in Wilmington, Delaware.
In a two-season career, Prentiss posted a 3–3 record with 10 strikeouts and a 5.31 ERA in 11 appearances, including seven starts, four complete games, and 57⅓ innings of work.
Prentiss died in his hometown of Wilmington, Delaware, at age 26 from Typhoid fever.