Clarence Edward "Babe" Twombly (January 18, 1896 – November 23, 1974) was a professional baseball player who was an outfielder in the Major Leagues from 1920 to 1921. He would play for the Chicago Cubs.
Babe was the younger brother of George Twombly who also played Major League Baseball.
Despite just 358 at bats at the Major League level with the Cubs, Babe had a career batting average of .304 and hit three big league home runs.